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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8936 | Proteinase K | proteinase K for tritirachium album,Protease K | Others |
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c... | |||
T62059 | Influenza A virus-IN-6 | ||
Influenza A virus-IN-6 (compound 16j) is a potent and selective inhibitor of influenza A virus (IC 50= 3.88 μM, CC50= 36.64 μM). Influenza A virus-IN-6 exhibits anti-IAV activity with low cytotoxicity. | |||
T72717 | Anti-IAV agent 1 | ||
Anti-IAV Agent 1-1a is an orally administered compound effective against the Influenza A virus (IAV), demonstrating inhibitory concentration 50 (IC50) values of 0.03 μM and 0.06 μM for the H1N1 strain and the Oseltamivir... | |||
T39778 | Influenza A virus-IN-1 | ||
Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV re... | |||
T62888 | Influenza A virus-IN-7 | ||
Influenza A virus-IN-7 (compound 16r) is a potent, orally active inhibitor of influenza A virus (IC50: 3.43 μM, CC50>100 μM). Influenza A virus-IN-7 is an anti-IAV agent with low cytotoxicity and inhibits viral RNA trans... | |||
T68413 | CBS1194 | ||
CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational cha... | |||
T61877 | Influenza A virus-IN-5 | ||
Influenza A virus-IN-5 (Compound 16e) is a highly potent and orally active agent against the influenza A virus (IAV), exhibiting an IC 50 of 1.29 μM. It effectively inhibits the transcription and replication of viral RNA... | |||
T78623 | Cobalt protoporphyrin IX | Reactive Oxygen Species | |
Cobalt Protoporphyrin IX serves as a potent, specific inducer of heme oxygenase-1 (HO-1) and demonstrates broad-spectrum antiviral effects against Influenza A virus (IAV) [1]. | |||
T79444 | HA-IN-1 | Influenza Virus | |
HA-IN-1 (compound 5g), a high-affinity Hemagglutinin (HA) ligand, targets the trypsin cleavage site of HA to inhibit HA-mediated membrane fusion and decrease pulmonary virus titer in vivo. This compound emerges as a prom... | |||
T60910 | RSV-IN-4 | ||
RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1]. | |||
T61217 | RSV-IN-3 | ||
RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1]. | |||
T77021 | Gedivumab | ||
Gedivumab (MHAA4549A; RG7745), a human monoclonal antibody, exhibits high specificity in targeting the influenza A virus (IAV) by binding to the highly conserved stem region of the IAV hemagglutinin protein. This interac... | |||
T62469 | RSV/IAV-IN-3 | ||
RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) (EC50: 2.92 μM) and influenza A virus (IAV) (EC50: 1.90 μM). RSV/IAV-IN-3 significantly inhibited luciferase activity in a dose-depend... | |||
T75938 | Z-VRPR-FMK TFA | ||
Z-VRPR-FMK (TFA), a selective and irreversible inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), is a tetrapeptide shown to provide protection against influenza A virus (IAV) infect... | |||
T77009 | Firivumab | ||
Firivumab (CT-P22; CT120), a human IgG1 monoclonal antibody targeting influenza A virus hemagglutinin (Anti-IAV HA), demonstrates neutralization capabilities against multiple strains including H1N1, H5N1, H6N1, H6N2, H8N... | |||
T36113 | Cobaltic Protoporphyrin IX chloride | Protoporphyrin IX cobaltic chloride | Autophagy |
Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a pote... | |||
T74762 | Influenza A virus-IN-8 | ||
Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and functions as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability. It has IC50 values of 6.7 nM for ... | |||
T36986 | Colletodiol | ||
Colletodiol is a fungal metabolite that has been found inD. grovesiiand has immunosuppressant and antiviral activities.1,2It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12... | |||
T38103 | Defensin HNP-3 (human) (trifluoroacetate salt) | ||
Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth o... |